I think you should be able to do it, however it will require you to manually change the CMDB Synch configuration back and foward between Dev and Prod.
It is something that is possible, but I do not recommend doing this on a regular basis. Is there a reason why you don't have a dev and prod instance of ADDM that you can use to sync to the two CMDB instances?
If you do need to switch CMDB Sync from one CMDB to another, have a look towards the bottom of this page of the documentation for how to do it.
Thanks Allan & Andherson for confirming this.
Client is looking for SIM POC & for that we need to sync with Dev CMDB.
Standing up a temporary ADDM appliance is not that difficult. I would recommend doing that rather than disruptinig your production ADDM appliance for a POC!