Is this hapen on one particular server? Are you using the bulk installer or manual update? If your doing a manual update. Can you look at the task manager for other setup programs? Or check out this link:
It has tip on how to resolve the error your getting. It's installshield error. So, it doesn't matter which OS is having the issue.
It happens on about 95% of our 64bit servers. Thanks for the links, I'll look into them now.