The short answer is it depends. What modifications are you making exactly? If you are referring to some type of "Find and Replace" or "Global Replace" feature, generally the answer is no. But you can do very specific things to multiple work orders at the same time like change the status, or changed the assigned technician.
Things that are not listed when you highlight multiple work orders and right-click...
Say changing the Type, Subtype, Category, or Adding a Note.
I assumed the answer was no so I plan on submitting this as an idea once you confirm that.
Thanks. I'd definitely add it as an Idea. Currently there are only a couple things that you can do to multiple work orders at once.